Showing posts with label Cancer. Show all posts
Showing posts with label Cancer. Show all posts

2.04.2016

Research gives me and many more Hope!

An interesting article on how animal research will help against the zika virus. You know transmitted via mosquitos as is the case for other diseases such as ebola or malaria. Animal research is much decried, rarely appreciated for what it does and mostly largely misunderstood by the general public.
That however does not mean it is useless, cruel or inadequate. You know when some say it, the type of research or results thereof, doesn't translate into human research or isn't applicable in humans they say it has no value. That is a wrong statement for through research we have learned about a disease, a virus or a physiological process or system.  That by itself is worth the endeavor. For some Hope is the only thing left in their fight for life! Let us not take that away too!

Now there is more going on behind the scene. Take a look at this 2008 article by Professor Colin Blakemore who teaches neuroscience at Oxford and Warwick Universities and is the former head of the UK's Medical Research Council. His conclusion speaks for itself: if we are to have any hope of treating such conditions (Alzheimer's, Multiple sclerosis,paralysis and schizophrenia), medical research needs every tool at its disposal. For everyone's sake, that must include animals. Today in 2016 this statement is as valid as it was when the article was written  and it shall remain so for the foreseeable future.
And as he did point out in the article those who oppose the use of animals in research are free to opt out from being dispensed drugs or treatments developed with the use of animals. Although I must say most of us, if vaccinated, have already been saved by animal research! Or as Lord Drayson has said it is time for us the public to ask ourselves the tough question about animal research Do I want those life saving medicines to be available to me, my family and friends? If yes then this research must continue to take place.

Another good read is this message by Hollis Cline President of the US Society for Neuroscience who reminds us the importance of basic research - such as in animal use research- in the drug development process. The eureka moment for drug development starts with a discovery in a lab. But basic research is also curiosity driven and therefore is able to produce unexpected results or greater understanding of biological processes. She warns that without a rich investment in basic research the drug development pipeline starves off.   I fully support her when she says that to accomplish the mission of improving human health we need to find the optimal balance of basic and translational research in the drug development pipeline and that means valuing and understanding every step in the process.
One of these crucial steps is animal testing let us not forget. Let us also take the time to understand its value and let us support it publicly. We all get to benefit from a healthy and well funded drug development pipeline.

I am not here to tell you what you should eat, wear, be sensitive about or not but as a father to two healthy kids and as a brother to a mentally handicapped child, let me tell you that in the light of the above hope I was referring to, it is by far not an exercise in futility to conduct animal research. It is a lifeline for many of us, who after years of giving care or of getting care have not given up the hope to one day see their loved ones, be they family, friends or total strangers cured from disease, disorder or affliction that has changed our and their lives forever. If that means conducting research on animals in an otherwise very regulated manner then you have my public support until the day it is no longer required. So let's make 2016 the year of public support to animal research. There are millions of us out there waiting for cures, a silent majority but not an immune one to the damages done by those opposing animal research. We have our voice and we will use it against you. Oh and if you happen to agree with me, please share this!


5.16.2012

Cancer in Memory Donna Summer RIP

None of us wants it and all of us wants it cured. In life there aren't many things we all can agree on.
Cancer I presume is one of them if my first sentence stands. There are many forms of cancer as we all know. I myself am of a fair complexity and I have freckles all over. Obviously shying away from exposure to direct sun is almost a primary reflex. We redheads generally turn red before getting a tan and only after having felt our skin burned first. In time I imagine that toxicologists have helped me and my consorts with easing some of that pain by means of dermatological creams and sunblocks. I am glad these weren't tested on me and that I could just grab my ointment straight from the pharmacy.

Talking of a complex disease, it should be said that there are advances taking place that are worth looking into. Take this article about In Vivo biology. It nicely describes how technology with the assistance of animal research, is helping discovering potential pathways previously not possible.

So yes medical science moves on and on different tracks simultaneously. It doesn't matter whether   they be in vivo, in vitro or computational models (not  an exhaustive methodology enumeration) or all combined. We all benefit from such advancements thanks to such institutions as the National Foundation for Cancer Research and the people working at its Center for Metastasis Research, where the four following questions are the basis of their proposed research studies:
(1) Why do some cancer cells metastasize while others do not?
(2) Why are some patients more susceptible to metastasis than others?
(3) What determines where cancer cells metastasize and their efficiency in
completing the seeding and growth at secondary sites?
(4) What are the signals that tumor cells give to and receive from their surrounding
environments?
 At some point in our lives we will be confronted with disease and chances are that Cancer is one of them. All of us will benefit from people like these. Look right here.

If you have taken the time to visit the NFCR pages above you know that the battle involved the discovery or breakthroughs of novel research tools and technologies, biomarkers or tools for identification of genetic phenomena, new drug candidates and cancer therapeutics, discovery of cancer related genes or proteins, clinical trials and much more.

A more complete list of breakthroughs is found here.

In memory of Donna Summer RIP

Now you decide whom you should DONATE some money to ! Just make sure it isn't PETA.